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KMID : 0361620190540020150
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Journal of the Korean Orthopaedic Association
2019 Volume.54 No. 2 p.150 ~ p.156
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Diagnostic Accuracy of Imaging Study and the Impact of Clinical Risk Factors on the Presence of Residual Tumor Following Unplanned Excision of Soft Tissue Sarcomas
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Oh Eun-Sun
Seo Sung-Wook
Jeong Jeong-Hwan
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Abstract
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Purpose: This study examined the diagnostic accuracy of an imaging study to find the factors that affect the presence of residual tumors after an unplanned excision of sarcomas.
Materials and Methods: Ninety-eight patients, who underwent a re-excision after unplanned surgery between January 2008 and December 2014, were enrolled in this study. Magnetic resonance imaging (MRI) was performed before reoperation in all patients. Positron emission tomography (PET)-computed tomography was performed on 54 patients. A wide re-excision and histology diagnosis were performed in all cases. The clinical variables were evaluated using univariate logistic regression and multivariate logistic regression.
Results: The presence of a deep-seated tumor increases the risk of remnant tumors (odds ratio: 3.21, p=0.02, 95% confidence interval: 1.25?8.30). The sensitivity for detecting residual tumors is high in MRI (sensitivity 0.79).
Conclusion: Deep-seated tumors have a significantly higher risk of remnant tumors. Because the negative predictive value of MRI and PET scans is very low, reoperation should be performed regardless of a negative result.
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KEYWORD
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sarcoma, soft tissue, unplanned excision, neoplasm, residual, re-excision
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